288 research outputs found

    Evaluation of spoken document retrieval for historic speech collections

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    The re-use of spoken word audio collections maintained by audiovisual archives is severely hindered by their generally limited access. The CHoral project, which is part of the CATCH program funded by the Dutch Research Council, aims to provide users of speech archives with online, instead of on-location, access to relevant fragments, instead of full documents. To meet this goal, a spoken document retrieval framework is being developed. In this paper the evaluation efforts undertaken so far to assess and improve various aspects of the framework are presented. These efforts include (i) evaluation of the automatically generated textual representations of the spoken word documents that enable word-based search, (ii) the development of measures to estimate the quality of the textual representations for use in information retrieval, and (iii) studies to establish the potential user groups of the to-be-developed technology, and the first versions of the user interface supporting online access to spoken word collections

    Resting-State Functional Connectivity Characteristics of Resilience to Traumatic Stress in Dutch Police Officers

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    BackgroundInsights into the neurobiological basis of resilience can have important implications for the prevention and treatment of stress-related disorders, especially in populations that are subjected to high-stress environments. Evaluating large-scale resting-state networks (RSNs) can provide information regarding resilient specific brain function which may be useful in understanding resilience. This study aimed to explore functional connectivity patterns specific for (high) resilience in Dutch policemen after exposure to multiple work-related traumatic events. We investigated resting-state functional connectivity (RSFC) of the salience network (SN), limbic network, and the default-mode network (DMN).MethodsResting-state functional MRI scans were obtained from trauma-exposed executive personnel of the Dutch police force and non-trauma-exposed recruits from the police academy. Participants were divided into three groups: a resilient group (n = 31; trauma exposure; no psychopathology), a vulnerable group (n = 32; trauma exposure, psychopathology), and a control group (n = 19; no trauma exposure, no psychopathology). RSFC of the three networks of interest was compared between these groups, using an independent component analysis and a dual regression approach.ResultsWe found decreased resilience-specific positive RSFC of the salience network with several prefrontal regions. The DMN and limbic network RFSC did not show resilience-specific patterns.ConclusionThis study shows a differential RSFC specific for resilient police officers. This differential RSFC may be related to a greater capacity for internal-focused thought and interoceptive awareness, allowing more effective higher-order responses to stress in highly resilient individuals

    Гарантоздатність як фундаментальний узагальнюючий та інтегруючий підхід

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    Представлені головні принципи та умови становлення і етапи розвитку фундаментальної теорії і практики узагальнюючих та інтегруючих концепцій гарантоздатності, починаючи з першої об’єднаної конференції двох наукових шкіл Дж. фон Неймана і Н. Вінера. Приведені основні положення розвитку теоретичних засад і результатів прикладних досліджень інтеграційних процесів безвідмовності (надійності), відмовостійкості та гарантоздатності інформаційно-управляючих комп’ютерних систем (ІУКС).Представлены главные принципы, условия становления и этапы развития фундаментальной теории и практики обобщающих и интегрирующих концепций гарантоспособности, начиная с первой объединённой конференции двух научных школ Дж. фон Неймана и Н. Винера. Приведены основные положения развития теоретических основ и результатов прикладных исследований интеграционных процессов безотказности (надёжности), отказоустойчивости и гарантоспособности информационно-управляющих компьютерных систем (ИУКС).The main principles and conditions of formation and stages of development of the fundamental theory and practice of the generalizing and integrating concepts of dependability were presented after the leadthrough the first joint conference of two scientific schools of J. von Neumann and N. Wiener. The basic aspects of development of theoretical principles and results of applied researches of integration processes of reliability (fail-safety)

    Malignant transformation of an abdominal inflammatory myofibroblastic tumor with distant metastases in a child

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    Inflammatory myofibroblastic tumors (IMT) are lesions that mostly affect young adults and children. The tumor is made up of myofibroblasts and a mixed inflammatory infiltrate and rarely undergoes malignant transformation. We present a case of a 13-year-old boy with a pelvic mass diagnosed as IMT which underwent malignant transformation and metastasised to the liver. We report the ultrasound, computed tomography (CT) and magnetic resonance (MR) findings of this rare disorder

    Validation of the Dutch Version of the Breakthrough Pain Assessment Tool in Patients With Cancer

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    Context: Essential for adequate management of breakthrough cancer pain is a combination of accurate (re-)assessment and a personalized treatment plan. The Breakthrough Pain Assessment Tool (BAT) has been proven to be a brief, multidimensional, reliable, and valid questionnaire for the assessment of breakthrough cancer pain. Objectives: The aim of this study was to examine the validity and reliability of the Dutch Language version of the BAT (BAT-DL) in patients with cancer. Methods: The BAT was forward-backward translated into the Dutch language. Thereafter, the psychometric properties of the BAT-DL were tested, that is factor structure, reliability (internal consistency and test-retest reliability), validity (content validity and construct validity), and the responsiveness to change. Results: The BAT-DL confirmed the two-factor structure in 170 patients with cancer: pain severity/impact factor and pain duration/medication efficacy factor. The Cronbach's alpha coefficient was 0.72, and the intraclass correlation for the test-retest reliability was 0.81. The BAT-DL showed to be able to differentiate between different group of patients and correlated significantly with the Brief Pain Inventory. In addition, the BAT-DL was capable to detect clinically important changes over time. Conclusion: The BAT-DL is a valid and reliable questionnaire to assess breakthrough pain in Dutch patients with cancer and is a relevant questionnaire for daily practice

    Square root singularity in the viscosity of neutral colloidal suspensions at large frequencies

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    The asymptotic frequency ω\omega, dependence of the dynamic viscosity of neutral hard sphere colloidal suspensions is shown to be of the form η0A(ϕ)(ωτP)1/2\eta_0 A(\phi) (\omega \tau_P)^{-1/2}, where A(ϕ)A(\phi) has been determined as a function of the volume fraction ϕ\phi, for all concentrations in the fluid range, η0\eta_0 is the solvent viscosity and τP\tau_P the P\'{e}clet time. For a soft potential it is shown that, to leading order steepness, the asymptotic behavior is the same as that for the hard sphere potential and a condition for the cross-over behavior to 1/ωτP1/\omega \tau_P is given. Our result for the hard sphere potential generalizes a result of Cichocki and Felderhof obtained at low concentrations and agrees well with the experiments of van der Werff et al, if the usual Stokes-Einstein diffusion coefficient D0D_0 in the Smoluchowski operator is consistently replaced by the short-time self diffusion coefficient Ds(ϕ)D_s(\phi) for non-dilute colloidal suspensions.Comment: 18 pages LaTeX, 1 postscript figur

    Maximising Synergy among Tropical Plant Systematists, Ecologists, and Evolutionary Biologists

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    Closer collaboration among ecologists, systematists, and evolutionary biologists working in tropical forests, centred on studies within long-term permanent plots, would be highly beneficial for their respective fields. With a key unifying theme of the importance of vouchered collection and precise identification of species, especially rare ones, we identify four priority areas where improving links between these communities could achieve significant progress in biodiversity and conservation science: (i) increasing the pace of species discovery; (ii) documenting species turnover across space and time; (iii) improving models of ecosystem change; and (iv) understanding the evolutionary assembly of communities and biomes
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